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Patrick Donal "Paddy" Maguire (born 20 April 1964, Belfast), is the patriarch and the head of the Maguire family, the most feared and therefore most respected of the local criminal families. His cherished wife is Mimi, and he has an identical twin brother called Noel, who is gay.

Patrick is extremely forceful and violent and his presence puts fear into most people on the Chatsworth Estate. For example, when he and his family enter the local pub, The Jockey, the customers sitting at the table beside the entrance clear the seat for them. He and his family are also drug dealers on the estate. He has a particular dislike for the Gallagher family, particularly Frank and Lip, which he has demonstrated on several occasions, both physically and verbally. However in more recent series, Paddy has begun to show a more compassionate side, and since series four, he has also become much more accepting of Lip Gallagher, as well as Karen Jackson, the wife of his oldest son Jamie. Paddy's identical twin brother Noel was credited as being played by Neil Grades, an anagram of actor Sean Gilder.

Despite his initial dislike of Frank Gallagher, this mind set was then turned after Paddy choked on a cashew nut in The Jockey and Frank acting out of morality (whilst very drunk, as per usual) perfomed the Heimlich manoeuvre, thus saving Paddy's life. Frank also saved Paddy's life again, stopping him from injecting himself with what would have been a lethal dose of heroin. Paddy now has some grudging respect for the Gallaghers.

Despite showing open contempt for higher education, Paddy has occasionally shown knowledge of certain literary subjects.

In Series 6, Paddy was briefly abducted by Maureen, the mother of a teenager who died after using his drugs, who in revenge repeatedly injected Paddy with heroin, causing him to become addicted to the substance. His attempts to conceal his new habit and deal with its effect on his life were a recurring theme of Series 6, with him finally going cold turkey later in the series, during which he had visions of his father Padriag.

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